Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--0.9 + vector arms; PvuII--19.0, 4.8 (doublet), 4.5, 3.9, 2.9, 1.8, 0.86, 0.60, 0.52; SalI-->23.0, 15.0, 0.56; HindIII--20.0, 12.0, 7.4, 4.5, 0.6; BglII-->23.0, 9.0, 2.8, 0.74. The insert contains the following restriction sites (nt from the 5' end): PvuII--89, 883; EcoRI--217. This is the cDNA for the transmembrane form of the protein. Contains the complete coding sequence (nt 116-865) plus 5' and 3'untranslated regions. |
References |
Wallner BP, et al. DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3. US Patent 4,956,281 dated Sep 11 1990
Wallner BP, et al. Primary strucure of lymphocyte function associated antigen-3 (LFA-3): the ligand of the T-lymphocyte CD2 glycoprotein. J. Exp. Med. 166: 923-932, 1987. PubMed: 3309127
Barbara Wallner, personal communication
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